Utilising time-lag focusing ultraviolet-matrix-assisted laser desorption/ionisation-mass spectrometry for the end group analysis of synthetic polymers

A. T. Jackson, H. T. Yates, C. I. Lindsay, Y. Didier, J. A. Segal, James Scrivens, G. Critchley, J. Brown

Research output: Contribution to journalReview articleResearchpeer-review

3 Citations (Scopus)

Abstract

Time-lag focusing matrix-assisted laser desorption/ionisation-mass spectrometry (MALDI-MS) has been employed to analyse synthetic polymers with average molecular weights between approximately 3500 and 12500 Da. Spectra are shown that demonstrate the improvement in resolution and sensitivity when time-lag focusing is used instead of prompt extraction techniques. A resolution of almost 9000 (FWHM) was obtained, in the reflectron mode of operation, for a poly(methyl methacrylate) (PMMA) sample with a relatively narrow dispersion. The data for PMMA polymers of industrial relevance easily enables the differentiation of many end groups as a consequence of the improved signal-to-noise and good mass accuracy when time-lag focusing is employed.

Original languageEnglish
JournalAnalusis
Volume26
Issue number10
Publication statusPublished - 1 Dec 1998

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Polymethyl Methacrylate
Ionization
Mass spectrometry
Desorption
Polymers
Lasers
Full width at half maximum
Molecular weight

Cite this

Jackson, A. T. ; Yates, H. T. ; Lindsay, C. I. ; Didier, Y. ; Segal, J. A. ; Scrivens, James ; Critchley, G. ; Brown, J. / Utilising time-lag focusing ultraviolet-matrix-assisted laser desorption/ionisation-mass spectrometry for the end group analysis of synthetic polymers. In: Analusis. 1998 ; Vol. 26, No. 10.
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abstract = "Time-lag focusing matrix-assisted laser desorption/ionisation-mass spectrometry (MALDI-MS) has been employed to analyse synthetic polymers with average molecular weights between approximately 3500 and 12500 Da. Spectra are shown that demonstrate the improvement in resolution and sensitivity when time-lag focusing is used instead of prompt extraction techniques. A resolution of almost 9000 (FWHM) was obtained, in the reflectron mode of operation, for a poly(methyl methacrylate) (PMMA) sample with a relatively narrow dispersion. The data for PMMA polymers of industrial relevance easily enables the differentiation of many end groups as a consequence of the improved signal-to-noise and good mass accuracy when time-lag focusing is employed.",
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Utilising time-lag focusing ultraviolet-matrix-assisted laser desorption/ionisation-mass spectrometry for the end group analysis of synthetic polymers. / Jackson, A. T.; Yates, H. T.; Lindsay, C. I.; Didier, Y.; Segal, J. A.; Scrivens, James; Critchley, G.; Brown, J.

In: Analusis, Vol. 26, No. 10, 01.12.1998.

Research output: Contribution to journalReview articleResearchpeer-review

TY - JOUR

T1 - Utilising time-lag focusing ultraviolet-matrix-assisted laser desorption/ionisation-mass spectrometry for the end group analysis of synthetic polymers

AU - Jackson, A. T.

AU - Yates, H. T.

AU - Lindsay, C. I.

AU - Didier, Y.

AU - Segal, J. A.

AU - Scrivens, James

AU - Critchley, G.

AU - Brown, J.

PY - 1998/12/1

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N2 - Time-lag focusing matrix-assisted laser desorption/ionisation-mass spectrometry (MALDI-MS) has been employed to analyse synthetic polymers with average molecular weights between approximately 3500 and 12500 Da. Spectra are shown that demonstrate the improvement in resolution and sensitivity when time-lag focusing is used instead of prompt extraction techniques. A resolution of almost 9000 (FWHM) was obtained, in the reflectron mode of operation, for a poly(methyl methacrylate) (PMMA) sample with a relatively narrow dispersion. The data for PMMA polymers of industrial relevance easily enables the differentiation of many end groups as a consequence of the improved signal-to-noise and good mass accuracy when time-lag focusing is employed.

AB - Time-lag focusing matrix-assisted laser desorption/ionisation-mass spectrometry (MALDI-MS) has been employed to analyse synthetic polymers with average molecular weights between approximately 3500 and 12500 Da. Spectra are shown that demonstrate the improvement in resolution and sensitivity when time-lag focusing is used instead of prompt extraction techniques. A resolution of almost 9000 (FWHM) was obtained, in the reflectron mode of operation, for a poly(methyl methacrylate) (PMMA) sample with a relatively narrow dispersion. The data for PMMA polymers of industrial relevance easily enables the differentiation of many end groups as a consequence of the improved signal-to-noise and good mass accuracy when time-lag focusing is employed.

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VL - 26

JO - Analusis

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