Weight loss interventions for adults with overweight/obesity and chronic musculoskeletal pain: a mixed methods systematic review

Lesley Cooper, Cormac Ryan, Louisa Ells, Sharon Hamilton, Gregory Atkinson, Kay Cooper, Mark I. Johnson, John P. Kirwan, Denis Martin

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Abstract

Worldwide prevalence of adult overweight and obesity is a growing public health issue. Adults with overweight/obesity often have chronic musculoskeletal pain. Using a mixed-methods review, we aimed to quantify the effectiveness and explore the appropriateness of weight-loss interventions for this population. Electronic databases were searched for studies published between 01/01/90-01/0716. The review included 14 randomised controlled trials that reported weight and pain outcomes and three qualitative studies that explored perceptions of adults with co-existing overweight/obesity and CMP. The random-effects pooled mean weight-loss was 4.9kg (95%CI:2.9,6.8) greater for intervention vs control. The pooled mean reduction in pain was 7.3/100units (95%CI:4.1,10.5) greater for intervention vs control. Study heterogeneity was substantial for weight loss (I2=95%, tau=±3.5kg) and pain change (I2=67%, tau=±4.1%). Meta-regression slopes for the predictors of study quality, mean age and baseline mean weight on mean study weight reduction were shallow and not statistically significant (P>0.05). The meta-regression slope between mean pain reduction and mean weight lost was shallow, and not statistically significant, -0.09kg per unit pain score change (95%CI:-0.21,0.40,p=0.54). Meta-synthesis of qualitative findings resulted in two synthesized findings; the importance of healthcare professionals understanding the effects of pain on ability to control weight, and developing management/education programmes that address comorbidity.
Original languageEnglish
Pages (from-to)989-1007
Number of pages19
JournalObesity Reviews
Volume19
Issue number7
DOIs
Publication statusPublished - 14 Feb 2018

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Musculoskeletal Pain
Chronic Pain
Weight Loss
Obesity
Pain
Weights and Measures
Cytidine Monophosphate
Aptitude
Comorbidity
Randomized Controlled Trials
Public Health
Databases
Delivery of Health Care
Education
Population

Cite this

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title = "Weight loss interventions for adults with overweight/obesity and chronic musculoskeletal pain: a mixed methods systematic review",
abstract = "Worldwide prevalence of adult overweight and obesity is a growing public health issue. Adults with overweight/obesity often have chronic musculoskeletal pain. Using a mixed-methods review, we aimed to quantify the effectiveness and explore the appropriateness of weight-loss interventions for this population. Electronic databases were searched for studies published between 01/01/90-01/0716. The review included 14 randomised controlled trials that reported weight and pain outcomes and three qualitative studies that explored perceptions of adults with co-existing overweight/obesity and CMP. The random-effects pooled mean weight-loss was 4.9kg (95{\%}CI:2.9,6.8) greater for intervention vs control. The pooled mean reduction in pain was 7.3/100units (95{\%}CI:4.1,10.5) greater for intervention vs control. Study heterogeneity was substantial for weight loss (I2=95{\%}, tau=±3.5kg) and pain change (I2=67{\%}, tau=±4.1{\%}). Meta-regression slopes for the predictors of study quality, mean age and baseline mean weight on mean study weight reduction were shallow and not statistically significant (P>0.05). The meta-regression slope between mean pain reduction and mean weight lost was shallow, and not statistically significant, -0.09kg per unit pain score change (95{\%}CI:-0.21,0.40,p=0.54). Meta-synthesis of qualitative findings resulted in two synthesized findings; the importance of healthcare professionals understanding the effects of pain on ability to control weight, and developing management/education programmes that address comorbidity.",
author = "Lesley Cooper and Cormac Ryan and Louisa Ells and Sharon Hamilton and Gregory Atkinson and Kay Cooper and Johnson, {Mark I.} and Kirwan, {John P.} and Denis Martin",
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Weight loss interventions for adults with overweight/obesity and chronic musculoskeletal pain: a mixed methods systematic review. / Cooper, Lesley; Ryan, Cormac; Ells, Louisa; Hamilton, Sharon; Atkinson, Gregory; Cooper, Kay; Johnson, Mark I.; Kirwan, John P.; Martin, Denis.

In: Obesity Reviews, Vol. 19, No. 7, 14.02.2018, p. 989-1007.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Cooper, Kay

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AU - Martin, Denis

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